Red LED Light Is Influenced by IL-6 to Promote the Migration Ability of Oral Squamous Cell Carcinoma Cell Line
Matsuo, Kenji Suzuki, Hiroaki Yatagai, Nanae Enomoto, Yui Kitayama, Midori Shigeoka, Manabu Kimoto, Akira Matsuomoto, Kosuke Komori, Takahide
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DOI/PMID/Link: 31327864
Abstract
Aim: The purpose of this study was to search for the influence of red LED light of oral squamous cell carcinoma cells (OSCC) Material & Methods: HSC-3 was irradiated with red LED light (630 nm/3 J). Proliferative capacity was analyzed using WST-1. Transwell migration assay, real-time PCR, and ELISA method were also used to analyze migratory ability. Conclusions: HSC-3 cells irradiated with red LED light showed increased migration ability. Interestingly, we clarified that the expression of Interleukin-6 (IL-6), which promotes the migratory ability of cancer cells, is induced.
| Year Published | 2019 |
|---|---|
| Country | Japan |
| Rank | Negative |
| Journal | Kobe Journal of Medical Sciences |
| Primary Topic | Mouth |
| Secondary Topic | Cancer |
| Tertiary Topic | Photodynamic Therapy |
| Model | Cell Culture |
| Wavelength (nm) | |
| Complement/Comparison |